BRD-K34776109_Glimepiride_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K34776109_Glimepiride_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM28 ADAM metallopeptidase domain 28
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BEX4 brain expressed, X-linked 4
CES1 carboxylesterase 1
COL11A1 collagen, type XI, alpha 1
DLK1 delta-like 1 homolog (Drosophila)
EGFL6 EGF-like-domain, multiple 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
PLAT plasminogen activator, tissue
POSTN periostin, osteoblast specific factor
PTGIS prostaglandin I2 (prostacyclin) synthase
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
THBS1 thrombospondin 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VNN1 vanin 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ACTB actin, beta
ADI1 acireductone dioxygenase 1
DPYSL2 dihydropyrimidinase-like 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM13A family with sequence similarity 13, member A
FLNA filamin A, alpha
GTF3A general transcription factor IIIA
GUSBP11 glucuronidase, beta pseudogene 11
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JCHAIN joining chain of multimeric IgA and IgM
KIF20A kinesin family member 20A
LIMCH1 LIM and calponin homology domains 1
LYZ lysozyme
RTN1 reticulon 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2