BRD-K34533029_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K34533029_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
APOD apolipoprotein D
CADM1 cell adhesion molecule 1
CD200 CD200 molecule
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
HEPH hephaestin
HMOX1 heme oxygenase 1
IVNS1ABP influenza virus NS1A binding protein
L1CAM L1 cell adhesion molecule
MAB21L2 mab-21-like 2 (C. elegans)
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NXN nucleoredoxin
PRAME preferentially expressed antigen in melanoma
RND3 Rho family GTPase 3
SAMD4A sterile alpha motif domain containing 4A
SDC3 syndecan 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
STX3 syntaxin 3
THBS1 thrombospondin 1

decreased expression

Symbol Name
ASCL1 achaete-scute family bHLH transcription factor 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CPM carboxypeptidase M
DHRS2 dehydrogenase/reductase (SDR family) member 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
H1F0 H1 histone family, member 0
KRT14 keratin 14, type I
LRRC17 leucine rich repeat containing 17
MARCKS myristoylated alanine-rich protein kinase C substrate
MET MET proto-oncogene, receptor tyrosine kinase
NR2F1 nuclear receptor subfamily 2, group F, member 1
PTGES prostaglandin E synthase
RAB25 RAB25, member RAS oncogene family
SET SET nuclear proto-oncogene
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TLR4 toll-like receptor 4
TPD52 tumor protein D52