BRD-K34533029_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

81 genes differentially expressed following the BRD-K34533029_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOA aldolase A, fructose-bisphosphate
ANXA5 annexin A5
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BST2 bone marrow stromal cell antigen 2
CCNG2 cyclin G2
CD8A CD8a molecule
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
DDIT4 DNA-damage-inducible transcript 4
EPHA3 EPH receptor A3
FKBP11 FK506 binding protein 11, 19 kDa
FUCA1 fucosidase, alpha-L- 1, tissue
GBP2 guanylate binding protein 2, interferon-inducible
GOLGA8A golgin A8 family, member A
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGF1R insulin-like growth factor 1 receptor
ISG15 ISG15 ubiquitin-like modifier
KDM3A lysine (K)-specific demethylase 3A
LEF1 lymphoid enhancer-binding factor 1
LUM lumican
MAOB monoamine oxidase B
MT1X metallothionein 1X
MT2A metallothionein 2A
MTUS1 microtubule associated tumor suppressor 1
NEFH neurofilament, heavy polypeptide
PEG3 paternally expressed 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVALB parvalbumin
SELL selectin L
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
VIM vimentin
VWF von Willebrand factor
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C6ORF62 chromosome 6 open reading frame 62
CD24 CD24 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLIC4 chloride intracellular channel 4
COPA coatomer protein complex, subunit alpha
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESRP1 epithelial splicing regulatory protein 1
EZR ezrin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FHL1 four and a half LIM domains 1
FZD5 frizzled class receptor 5
IL13RA1 interleukin 13 receptor, alpha 1
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA6 integrin, alpha 6
MBNL2 muscleblind-like splicing regulator 2
MCL1 myeloid cell leukemia 1
MEIS1 Meis homeobox 1
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RBP1 retinol binding protein 1, cellular
RNF167 ring finger protein 167
S100P S100 calcium binding protein P
SCARB2 scavenger receptor class B, member 2
SEPT2 septin 2
SFRP1 secreted frizzled-related protein 1
SON SON DNA binding protein
SOX4 SRY (sex determining region Y)-box 4
SRPR signal recognition particle receptor (docking protein)
SRSF1 serine/arginine-rich splicing factor 1
SST somatostatin
STX1A syntaxin 1A (brain)
TCF21 transcription factor 21
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
VAMP3 vesicle-associated membrane protein 3
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta