BRD-K34495954_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K34495954_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATF3 activating transcription factor 3
BLNK B-cell linker
CA2 carbonic anhydrase II
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC25B cell division cycle 25B
CES1 carboxylesterase 1
CLCA4 chloride channel accessory 4
COL4A5 collagen, type IV, alpha 5
CSTA cystatin A (stefin A)
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
EMP1 epithelial membrane protein 1
EXT1 exostosin glycosyltransferase 1
FGFR2 fibroblast growth factor receptor 2
FOXF1 forkhead box F1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
MANSC1 MANSC domain containing 1
MDFIC MyoD family inhibitor domain containing
P3H2 prolyl 3-hydroxylase 2
PTPRK protein tyrosine phosphatase, receptor type, K
S100A8 S100 calcium binding protein A8
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SYNM synemin, intermediate filament protein
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMSB15A thymosin beta 15a
TRIM2 tripartite motif containing 2
WLS wntless Wnt ligand secretion mediator

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
BEX1 brain expressed, X-linked 1
C6ORF62 chromosome 6 open reading frame 62
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEMIP cell migration inducing protein, hyaluronan binding
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
FBXL12 F-box and leucine-rich repeat protein 12
HSPA8 heat shock 70kDa protein 8
MATN2 matrilin 2
MFAP5 microfibrillar associated protein 5
MYB v-myb avian myeloblastosis viral oncogene homolog
PEG3 paternally expressed 3
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PSPH phosphoserine phosphatase
RPS11 ribosomal protein S11
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TSPAN8 tetraspanin 8