BRD-K34415467_Trimethobenzamide hydrochloride_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K34415467_Trimethobenzamide hydrochloride_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ASS1 argininosuccinate synthase 1
ATG3 autophagy related 3
CST3 cystatin C
ESR1 estrogen receptor 1
HIST1H2BG histone cluster 1, H2bg
KIAA0100 KIAA0100
PAN2 PAN2 poly(A) specific ribonuclease subunit
PI3 peptidase inhibitor 3, skin-derived
PRR7 proline rich 7 (synaptic)
TFF1 trefoil factor 1

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AHR aryl hydrocarbon receptor
APOD apolipoprotein D
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ATF1 activating transcription factor 1
AZIN1 antizyme inhibitor 1
BICC1 BicC family RNA binding protein 1
BTG3 BTG family, member 3
C3 complement component 3
C7 complement component 7
CASD1 CAS1 domain containing 1
CFD complement factor D (adipsin)
CPM carboxypeptidase M
DPYSL2 dihydropyrimidinase-like 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1AX eukaryotic translation initiation factor 1A, X-linked
FABP4 fatty acid binding protein 4, adipocyte
FGG fibrinogen gamma chain
FHL1 four and a half LIM domains 1
FLRT2 fibronectin leucine rich transmembrane protein 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GJA1 gap junction protein, alpha 1, 43kDa
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HACD2 3-hydroxyacyl-CoA dehydratase 2
IGFBP7 insulin-like growth factor binding protein 7
KLF5 Kruppel-like factor 5 (intestinal)
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MATN2 matrilin 2
MBP myelin basic protein
NRIP1 nuclear receptor interacting protein 1
PEG10 paternally expressed 10
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PRNP prion protein
RECK reversion-inducing-cysteine-rich protein with kazal motifs
SGCE sarcoglycan, epsilon
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC38A1 solute carrier family 38, member 1
SPTSSA serine palmitoyltransferase, small subunit A
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
WWTR1 WW domain containing transcription regulator 1