BRD-K34332553_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K34332553_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
ADIRF adipogenesis regulatory factor
AMIGO2 adhesion molecule with Ig-like domain 2
CHIC2 cysteine-rich hydrophobic domain 2
CXCL13 chemokine (C-X-C motif) ligand 13
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EREG epiregulin
EVI2A ecotropic viral integration site 2A
FNTA farnesyltransferase, CAAX box, alpha
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
HBP1 HMG-box transcription factor 1
HECA headcase homolog (Drosophila)
HMOX1 heme oxygenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
KDM3A lysine (K)-specific demethylase 3A
KIAA1033 KIAA1033
KIF14 kinesin family member 14
LOC100272216 uncharacterized LOC100272216
MELK maternal embryonic leucine zipper kinase
MTA1 metastasis associated 1
MYO6 myosin VI
N4BP2L2 NEDD4 binding protein 2-like 2
NKTR natural killer cell triggering receptor
PHIP pleckstrin homology domain interacting protein
RB1CC1 RB1-inducible coiled-coil 1
RIOK3 RIO kinase 3
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFRP4 secreted frizzled-related protein 4
SLC38A1 solute carrier family 38, member 1
SULF1 sulfatase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKAP12 A kinase (PRKA) anchor protein 12
AMD1 adenosylmethionine decarboxylase 1
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AQP3 aquaporin 3 (Gill blood group)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C3 complement component 3
CBR1 carbonyl reductase 1
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD59 CD59 molecule, complement regulatory protein
CHPT1 choline phosphotransferase 1
CIAPIN1 cytokine induced apoptosis inhibitor 1
DDIT4 DNA-damage-inducible transcript 4
ENO1 enolase 1, (alpha)
FAM57A family with sequence similarity 57, member A
GSN gelsolin
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ISG15 ISG15 ubiquitin-like modifier
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAT2A methionine adenosyltransferase II, alpha
NEFL neurofilament, light polypeptide
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX3-1 NK3 homeobox 1
PDLIM4 PDZ and LIM domain 4
PI3 peptidase inhibitor 3, skin-derived
PKM pyruvate kinase, muscle
PPIF peptidylprolyl isomerase F
PRMT1 protein arginine methyltransferase 1
PTX3 pentraxin 3, long
RHOB ras homolog family member B
SCG2 secretogranin II
SDC4 syndecan 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH3BP4 SH3-domain binding protein 4
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
SPATS2L spermatogenesis associated, serine-rich 2-like
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNC tenascin C
UGCG UDP-glucose ceramide glucosyltransferase
WFDC2 WAP four-disulfide core domain 2