BRD-K34332553_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K34332553_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
ATF4 activating transcription factor 4
C6ORF62 chromosome 6 open reading frame 62
CAST calpastatin
FAM129A family with sequence similarity 129, member A
FLRT2 fibronectin leucine rich transmembrane protein 2
IGFBP7 insulin-like growth factor binding protein 7
LEF1 lymphoid enhancer-binding factor 1
MT1M metallothionein 1M
RGCC regulator of cell cycle
TSPAN7 tetraspanin 7
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADI1 acireductone dioxygenase 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
BST2 bone marrow stromal cell antigen 2
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
METRN meteorin, glial cell differentiation regulator
MMP7 matrix metallopeptidase 7
PROM1 prominin 1
RBPMS RNA binding protein with multiple splicing
TM4SF1 transmembrane 4 L six family member 1
TMEM45A transmembrane protein 45A