BRD-K34170797_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K34170797_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABLIM1 actin binding LIM protein 1
ALCAM activated leukocyte cell adhesion molecule
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BANK1 B-cell scaffold protein with ankyrin repeats 1
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDAH1 dimethylarginine dimethylaminohydrolase 1
DPYSL2 dihydropyrimidinase-like 2
EIF4B eukaryotic translation initiation factor 4B
FST follistatin
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGFBP7 insulin-like growth factor binding protein 7
IL1R2 interleukin 1 receptor, type II
LYZ lysozyme
MMP7 matrix metallopeptidase 7
MORC4 MORC family CW-type zinc finger 4
NNMT nicotinamide N-methyltransferase
P3H2 prolyl 3-hydroxylase 2
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PHGDH phosphoglycerate dehydrogenase
RHOB ras homolog family member B
RPL37A ribosomal protein L37a
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TSC22D3 TSC22 domain family, member 3
TXN thioredoxin
VNN1 vanin 1
WDTC1 WD and tetratricopeptide repeats 1
WNT5A wingless-type MMTV integration site family, member 5A
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ASPN asporin
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF5B eukaryotic translation initiation factor 5B
GNAS GNAS complex locus
L1CAM L1 cell adhesion molecule
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
NCAM1 neural cell adhesion molecule 1
PCBP2 poly(rC) binding protein 2
PTMA prothymosin, alpha
RBMS1 RNA binding motif, single stranded interacting protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SOX11 SRY (sex determining region Y)-box 11
SST somatostatin
TGFBR3 transforming growth factor, beta receptor III
TGM2 transglutaminase 2