BRD-K33882852_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

109 genes differentially expressed following the BRD-K33882852_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADGRG6 adhesion G protein-coupled receptor G6
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA3 annexin A3
AREG amphiregulin
ATF3 activating transcription factor 3
BST2 bone marrow stromal cell antigen 2
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CFD complement factor D (adipsin)
CHIC2 cysteine-rich hydrophobic domain 2
CRABP1 cellular retinoic acid binding protein 1
CXCL11 chemokine (C-X-C motif) ligand 11
CYR61 cysteine-rich, angiogenic inducer, 61
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
EZR ezrin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM49A family with sequence similarity 49, member A
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FOXF1 forkhead box F1
GEM GTP binding protein overexpressed in skeletal muscle
HES1 hes family bHLH transcription factor 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER3 immediate early response 3
IFITM1 interferon induced transmembrane protein 1
IGL immunoglobulin lambda locus
ISG20 interferon stimulated exonuclease gene 20kDa
JUNB jun B proto-oncogene
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MFSD10 major facilitator superfamily domain containing 10
MGP matrix Gla protein
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEBL nebulette
NR4A1 nuclear receptor subfamily 4, group A, member 1
OASL 2'-5'-oligoadenylate synthetase-like
PHACTR2 phosphatase and actin regulator 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PROM1 prominin 1
S100P S100 calcium binding protein P
SEC14L1 SEC14-like 1 (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3GLB1 SH3-domain GRB2-like endophilin B1
SIK1 salt-inducible kinase 1
SOX9 SRY (sex determining region Y)-box 9
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STK39 serine threonine kinase 39
TGFA transforming growth factor, alpha
TGIF1 TGFB-induced factor homeobox 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
ANKRD10 ankyrin repeat domain 10
ARID5B AT rich interactive domain 5B (MRF1-like)
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BCHE butyrylcholinesterase
CAST calpastatin
CD14 CD14 molecule
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCLK1 doublecortin-like kinase 1
FASTKD5 FAST kinase domains 5
FLG filaggrin
GJA1 gap junction protein, alpha 1, 43kDa
GLS glutaminase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA2 heat shock 70kDa protein 2
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCTD12 potassium channel tetramerization domain containing 12
LSP1 lymphocyte-specific protein 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGED1 melanoma antigen family D1
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
METTL3 methyltransferase like 3
MXRA5 matrix-remodelling associated 5
NUP62 nucleoporin 62kDa
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARP2 poly (ADP-ribose) polymerase 2
PCTP phosphatidylcholine transfer protein
PLAGL1 pleiomorphic adenoma gene-like 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRKCA protein kinase C, alpha
PTP4A2 protein tyrosine phosphatase type IVA, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPINK1 serine peptidase inhibitor, Kazal type 1
SYBU syntabulin (syntaxin-interacting)
TMEM45A transmembrane protein 45A
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UNC119B unc-119 homolog B (C. elegans)
VCAN versican
ZNF302 zinc finger protein 302