BRD-K33864865_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K33864865_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
AMDHD2 amidohydrolase domain containing 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
CD24 CD24 molecule
CD9 CD9 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN3 claudin 3
CORO1A coronin, actin binding protein, 1A
COTL1 coactosin-like F-actin binding protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EGR3 early growth response 3
EMP1 epithelial membrane protein 1
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FLNA filamin A, alpha
GPI glucose-6-phosphate isomerase
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HLA-B major histocompatibility complex, class I, B
IFRD1 interferon-related developmental regulator 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
JUNB jun B proto-oncogene
KRT81 keratin 81, type II
LTF lactotransferrin
MAGED1 melanoma antigen family D1
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
NPY neuropeptide Y
PDE4B phosphodiesterase 4B, cAMP-specific
RNF167 ring finger protein 167
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SRGN serglycin
TMEM134 transmembrane protein 134
TMEM8A transmembrane protein 8A
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WSB1 WD repeat and SOCS box containing 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ATF5 activating transcription factor 5
BCL2 B-cell CLL/lymphoma 2
BST2 bone marrow stromal cell antigen 2
CD93 CD93 molecule
CDCA4 cell division cycle associated 4
CES1 carboxylesterase 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
FXYD6 FXYD domain containing ion transport regulator 6
GPNMB glycoprotein (transmembrane) nmb
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HN1 hematological and neurological expressed 1
HSPB8 heat shock 22kDa protein 8
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
MATN2 matrilin 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
PEG3 paternally expressed 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMC4 structural maintenance of chromosomes 4
STS steroid sulfatase (microsomal), isozyme S
SUMO2 small ubiquitin-like modifier 2