BRD-K33720404_-666_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K33720404_-666_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
CHPT1 choline phosphotransferase 1
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
IGFBP3 insulin-like growth factor binding protein 3
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KRT18 keratin 18, type I
KRT7 keratin 7, type II
KRT8 keratin 8, type II
LIMCH1 LIM and calponin homology domains 1
LYZ lysozyme
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MUC5B mucin 5B, oligomeric mucus/gel-forming
OLFM4 olfactomedin 4
PDGFC platelet derived growth factor C
PHGDH phosphoglycerate dehydrogenase
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP1 secreted frizzled-related protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TBX3 T-box 3
XPOT exportin, tRNA

decreased expression

Symbol Name
AQP1 aquaporin 1 (Colton blood group)
COL5A1 collagen, type V, alpha 1
EREG epiregulin
G0S2 G0/G1 switch 2
GAL galanin/GMAP prepropeptide
HSPA2 heat shock 70kDa protein 2