BRD-K33583600_ISOLIQUIRITIGENIN_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K33583600_ISOLIQUIRITIGENIN_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C2 aldo-keto reductase family 1, member C2
BAG3 BCL2-associated athanogene 3
C3ORF14 chromosome 3 open reading frame 14
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FADS1 fatty acid desaturase 1
FHL2 four and a half LIM domains 2
GATA3 GATA binding protein 3
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
MT1M metallothionein 1M
PDGFA platelet-derived growth factor alpha polypeptide
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
DDIT4 DNA-damage-inducible transcript 4
GOLGA8A golgin A8 family, member A
HES1 hes family bHLH transcription factor 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KRT18 keratin 18, type I
LUM lumican
RGS1 regulator of G-protein signaling 1
TMEM2 transmembrane protein 2