BRD-K33312228_halometasone_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K33312228_halometasone_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADGRG2 adhesion G protein-coupled receptor G2
ANPEP alanyl (membrane) aminopeptidase
ASMTL acetylserotonin O-methyltransferase-like
BCL3 B-cell CLL/lymphoma 3
CHRDL1 chordin-like 1
CLIC5 chloride intracellular channel 5
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
EDN3 endothelin 3
EDNRB endothelin receptor type B
F3 coagulation factor III (thromboplastin, tissue factor)
FASN fatty acid synthase
FGFR4 fibroblast growth factor receptor 4
FKBP5 FK506 binding protein 5
HOMER2 homer scaffolding protein 2
HSPA1A heat shock 70kDa protein 1A
KIAA1324 KIAA1324
KRT5 keratin 5, type II
LDLR low density lipoprotein receptor
LIMS1 LIM and senescent cell antigen-like domains 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
OLFML3 olfactomedin-like 3
PDIA5 protein disulfide isomerase family A, member 5
POSTN periostin, osteoblast specific factor
PXN paxillin
RAP1GAP RAP1 GTPase activating protein
REC8 REC8 meiotic recombination protein
RPL37A ribosomal protein L37a
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC44A4 solute carrier family 44, member 4
SYBU syntabulin (syntaxin-interacting)
TPPP3 tubulin polymerization-promoting protein family member 3
TUBA4A tubulin, alpha 4a
UGDH UDP-glucose 6-dehydrogenase
ZBTB16 zinc finger and BTB domain containing 16
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA10 annexin A10
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CADM1 cell adhesion molecule 1
CCDC86 coiled-coil domain containing 86
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GHR growth hormone receptor
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GSTM3 glutathione S-transferase mu 3 (brain)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
KRT7 keratin 7, type II
LIMCH1 LIM and calponin homology domains 1
MAP7 microtubule-associated protein 7
MET MET proto-oncogene, receptor tyrosine kinase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLA2G16 phospholipase A2, group XVI
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLS1 plastin 1
RHOB ras homolog family member B
SESN1 sestrin 1
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
VNN1 vanin 1