BRD-K33116223_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K33116223_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ASNS asparagine synthetase (glutamine-hydrolyzing)
BID BH3 interacting domain death agonist
CD1E CD1e molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DDIT4 DNA-damage-inducible transcript 4
FADS1 fatty acid desaturase 1
FGL2 fibrinogen-like 2
HBD hemoglobin, delta
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
LXN latexin
LYZ lysozyme
MMP7 matrix metallopeptidase 7
NNMT nicotinamide N-methyltransferase
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PCGF2 polycomb group ring finger 2
PDZK1IP1 PDZK1 interacting protein 1
PLAT plasminogen activator, tissue
PSPH phosphoserine phosphatase
PTGIS prostaglandin I2 (prostacyclin) synthase
PYCARD PYD and CARD domain containing
QPCT glutaminyl-peptide cyclotransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RTN1 reticulon 1
SIRPA signal-regulatory protein alpha
SRGN serglycin
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIB2 tribbles pseudokinase 2
TXNIP thioredoxin interacting protein
VCAN versican
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
ANGPT1 angiopoietin 1
BAALC brain and acute leukemia, cytoplasmic
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CANT1 calcium activated nucleotidase 1
CCND1 cyclin D1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GRB7 growth factor receptor-bound protein 7
IQGAP1 IQ motif containing GTPase activating protein 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0125 KIAA0125
KRT14 keratin 14, type I
LDLR low density lipoprotein receptor
LPL lipoprotein lipase
MYO6 myosin VI
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NRCAM neuronal cell adhesion molecule
NUP62 nucleoporin 62kDa
PAM peptidylglycine alpha-amidating monooxygenase
PDLIM1 PDZ and LIM domain 1
PFN2 profilin 2
PKM pyruvate kinase, muscle
PLAGL1 pleiomorphic adenoma gene-like 1
PRKCD protein kinase C, delta
RDX radixin
S100A2 S100 calcium binding protein A2
SATB1 SATB homeobox 1
SEPP1 selenoprotein P, plasma, 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
STK26 serine/threonine protein kinase 26
SYNJ2 synaptojanin 2
TES testin LIM domain protein
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNC tenascin C
TPM4 tropomyosin 4
TSPAN3 tetraspanin 3
TTC3 tetratricopeptide repeat domain 3
TWIST1 twist family bHLH transcription factor 1
WASL Wiskott-Aldrich syndrome-like
ZIC1 Zic family member 1