BRD-K33116223_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K33116223_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARMCX1 armadillo repeat containing, X-linked 1
BEX1 brain expressed, X-linked 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CECR1 cat eye syndrome chromosome region, candidate 1
COL1A2 collagen, type I, alpha 2
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
ERLIN1 ER lipid raft associated 1
FAM49A family with sequence similarity 49, member A
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GREM1 gremlin 1, DAN family BMP antagonist
HBB hemoglobin, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HSPA13 heat shock protein 70kDa family, member 13
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
JCHAIN joining chain of multimeric IgA and IgM
LDB2 LIM domain binding 2
LMO2 LIM domain only 2 (rhombotin-like 1)
LPAR6 lysophosphatidic acid receptor 6
MUC16 mucin 16, cell surface associated
MZB1 marginal zone B and B1 cell-specific protein
NREP neuronal regeneration related protein
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLK2 polo-like kinase 2
RGS5 regulator of G-protein signaling 5
SCGB2A1 secretoglobin, family 2A, member 1
SERINC5 serine incorporator 5
SESN1 sestrin 1
TMEM255A transmembrane protein 255A
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WARS tryptophanyl-tRNA synthetase
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
APOD apolipoprotein D
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
CRIP1 cysteine-rich protein 1 (intestinal)
CTGF connective tissue growth factor
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP6 dual specificity phosphatase 6
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
GAL galanin/GMAP prepropeptide
GMDS GDP-mannose 4,6-dehydratase
HSPB8 heat shock 22kDa protein 8
IFI6 interferon, alpha-inducible protein 6
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
MAP7 microtubule-associated protein 7
MT1X metallothionein 1X
MTCL1 microtubule crosslinking factor 1
MYCBP MYC binding protein
NDRG1 N-myc downstream regulated 1
NNMT nicotinamide N-methyltransferase
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100A2 S100 calcium binding protein A2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SORBS1 sorbin and SH3 domain containing 1
SOX9 SRY (sex determining region Y)-box 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STOM stomatin
TCL1A T-cell leukemia/lymphoma 1A
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1