BRD-K33045404_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K33045404_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACAA2 acetyl-CoA acyltransferase 2
AGTR1 angiotensin II receptor, type 1
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
BCL2A1 BCL2-related protein A1
CCL20 chemokine (C-C motif) ligand 20
CEMIP cell migration inducing protein, hyaluronan binding
CIRBP cold inducible RNA binding protein
CTSZ cathepsin Z
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DPYSL3 dihydropyrimidinase-like 3
DSTN destrin (actin depolymerizing factor)
FABP4 fatty acid binding protein 4, adipocyte
FN1 fibronectin 1
FTH1 ferritin, heavy polypeptide 1
G0S2 G0/G1 switch 2
GDF15 growth differentiation factor 15
GSN gelsolin
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IL1B interleukin 1, beta
ISG15 ISG15 ubiquitin-like modifier
KRT18 keratin 18, type I
KRT23 keratin 23, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MLPH melanophilin
NEFH neurofilament, heavy polypeptide
PSPH phosphoserine phosphatase
RHOB ras homolog family member B
S100A10 S100 calcium binding protein A10
S100A4 S100 calcium binding protein A4
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
STC2 stanniocalcin 2
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1
TSPAN8 tetraspanin 8
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
CCND1 cyclin D1
CHN1 chimerin 1
EGFR epidermal growth factor receptor
GLUL glutamate-ammonia ligase
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
PCDH7 protocadherin 7
PLTP phospholipid transfer protein
PODXL podocalyxin-like
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A9 S100 calcium binding protein A9
SFRP1 secreted frizzled-related protein 1
ZEB1 zinc finger E-box binding homeobox 1
ZFP36L2 ZFP36 ring finger protein-like 2