BRD-K32896438_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K32896438_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOLD1 apolipoprotein L domain containing 1
ATF3 activating transcription factor 3
BTG1 B-cell translocation gene 1, anti-proliferative
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EXOSC4 exosome component 4
GADD45B growth arrest and DNA-damage-inducible, beta
HIST1H1C histone cluster 1, H1c
HIST1H2AE histone cluster 1, H2ae
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HSPA1A heat shock 70kDa protein 1A
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
LEF1 lymphoid enhancer-binding factor 1
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIL3 nuclear factor, interleukin 3 regulated
NOTCH2NL notch 2 N-terminal like
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TSC22D3 TSC22 domain family, member 3
VCAN versican

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
FHOD3 formin homology 2 domain containing 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
MEIS2 Meis homeobox 2
PAX5 paired box 5
PEG10 paternally expressed 10
SDC1 syndecan 1
STK26 serine/threonine protein kinase 26