BRD-K32821942_Azathioprine;446-86-6_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

111 genes differentially expressed following the BRD-K32821942_Azathioprine;446-86-6_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADIRF adipogenesis regulatory factor
AGA aspartylglucosaminidase
AMDHD2 amidohydrolase domain containing 2
APOD apolipoprotein D
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASPH aspartate beta-hydroxylase
BBX bobby sox homolog (Drosophila)
BHLHE41 basic helix-loop-helix family, member e41
BTBD3 BTB (POZ) domain containing 3
CD40 CD40 molecule, TNF receptor superfamily member 5
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CKLF chemokine-like factor
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDIT3 DNA-damage-inducible transcript 3
DSG2 desmoglein 2
DUSP6 dual specificity phosphatase 6
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FST follistatin
GDF15 growth differentiation factor 15
GOLGA8A golgin A8 family, member A
GTPBP8 GTP-binding protein 8 (putative)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOXB7 homeobox B7
IER5 immediate early response 5
IL6ST interleukin 6 signal transducer
KCNK1 potassium channel, two pore domain subfamily K, member 1
KLHL24 kelch-like family member 24
KRT19 keratin 19, type I
LPAR6 lysophosphatidic acid receptor 6
MDK midkine (neurite growth-promoting factor 2)
MFAP5 microfibrillar associated protein 5
MUC4 mucin 4, cell surface associated
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NDNF neuron-derived neurotrophic factor
NPTX2 neuronal pentraxin II
NT5E 5'-nucleotidase, ecto (CD73)
NUCB2 nucleobindin 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PIP prolactin-induced protein
PLAT plasminogen activator, tissue
PLIN2 perilipin 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
TFF1 trefoil factor 1
TRIB3 tribbles pseudokinase 3
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
VEZF1 vascular endothelial zinc finger 1
WDTC1 WD and tetratricopeptide repeats 1
XIST X inactive specific transcript (non-protein coding)
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANGPT1 angiopoietin 1
ARG1 arginase 1
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CKB creatine kinase, brain
CLU clusterin
COCH cochlin
CST7 cystatin F (leukocystatin)
CTSG cathepsin G
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB4A defensin, beta 4A
DHCR7 7-dehydrocholesterol reductase
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EXOSC4 exosome component 4
FAM198B family with sequence similarity 198, member B
FASN fatty acid synthase
FMO2 flavin containing monooxygenase 2 (non-functional)
GATA2 GATA binding protein 2
GRWD1 glutamate-rich WD repeat containing 1
HAL histidine ammonia-lyase
HMOX1 heme oxygenase 1
INTS3 integrator complex subunit 3
KDM5D lysine (K)-specific demethylase 5D
KIAA0125 KIAA0125
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LEFTY1 left-right determination factor 1
LOXL1 lysyl oxidase-like 1
LYST lysosomal trafficking regulator
MTA1 metastasis associated 1
NEBL nebulette
NPY1R neuropeptide Y receptor Y1
PITX1 paired-like homeodomain 1
PLAGL2 pleiomorphic adenoma gene-like 2
PPIF peptidylprolyl isomerase F
PPL periplakin
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RGS1 regulator of G-protein signaling 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A9 S100 calcium binding protein A9
SERBP1 SERPINE1 mRNA binding protein 1
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SQLE squalene epoxidase
SRSF1 serine/arginine-rich splicing factor 1
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TUBA4A tubulin, alpha 4a
UBE2S ubiquitin-conjugating enzyme E2S