BRD-K32536677_AGK-2_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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63 genes differentially expressed following the BRD-K32536677_AGK-2_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
APOE apolipoprotein E
ARG2 arginase 2
C10ORF10 chromosome 10 open reading frame 10
CCL5 chemokine (C-C motif) ligand 5
CD36 CD36 molecule (thrombospondin receptor)
CLEC2B C-type lectin domain family 2, member B
CSNK1E casein kinase 1, epsilon
CX3CR1 chemokine (C-X3-C motif) receptor 1
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FST follistatin
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HDGFRP3 hepatoma-derived growth factor, related protein 3
HNMT histamine N-methyltransferase
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
KLRK1 killer cell lectin-like receptor subfamily K, member 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MTSS1 metastasis suppressor 1
NES nestin
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PTN pleiotrophin
S100A6 S100 calcium binding protein A6
S100A9 S100 calcium binding protein A9
SDC2 syndecan 2
SETBP1 SET binding protein 1
SOX9 SRY (sex determining region Y)-box 9
THBS4 thrombospondin 4
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TUBB2A tubulin, beta 2A class IIa
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ALCAM activated leukocyte cell adhesion molecule
BCL6 B-cell CLL/lymphoma 6
CAV1 caveolin 1, caveolae protein, 22kDa
CD302 CD302 molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
DCN decorin
EIF5A eukaryotic translation initiation factor 5A
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FZD6 frizzled class receptor 6
GCH1 GTP cyclohydrolase 1
GPI glucose-6-phosphate isomerase
ITM2C integral membrane protein 2C
KLK10 kallikrein-related peptidase 10
LACTB2 lactamase, beta 2
LMO3 LIM domain only 3 (rhombotin-like 2)
LXN latexin
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MFAP3L microfibrillar-associated protein 3-like
MSLN mesothelin
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PON2 paraoxonase 2
PSENEN presenilin enhancer gamma secretase subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC38A1 solute carrier family 38, member 1
SNX13 sorting nexin 13
TES testin LIM domain protein
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17