BRD-K32536677_-666_SW620_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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58 genes differentially expressed following the BRD-K32536677_-666_SW620_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA4 annexin A4
BHLHE41 basic helix-loop-helix family, member e41
CADM1 cell adhesion molecule 1
COL1A2 collagen, type I, alpha 2
DCN decorin
DLD dihydrolipoamide dehydrogenase
EVI2A ecotropic viral integration site 2A
F11R F11 receptor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIRA histone cell cycle regulator
IL32 interleukin 32
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LAMB3 laminin, beta 3
LUM lumican
MKNK1 MAP kinase interacting serine/threonine kinase 1
MME membrane metallo-endopeptidase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBPC1 myosin binding protein C, slow type
NEB nebulin
PAPD7 PAP associated domain containing 7
PDE4B phosphodiesterase 4B, cAMP-specific
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RGCC regulator of cell cycle
S100A13 S100 calcium binding protein A13
S100A8 S100 calcium binding protein A8
SCGB2A1 secretoglobin, family 2A, member 1
SHB Src homology 2 domain containing adaptor protein B
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SNX7 sorting nexin 7
STAR steroidogenic acute regulatory protein
STS steroid sulfatase (microsomal), isozyme S
TFRC transferrin receptor
THBS2 thrombospondin 2
UPP1 uridine phosphorylase 1
VEGFA vascular endothelial growth factor A
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
AGR2 anterior gradient 2
CXCL14 chemokine (C-X-C motif) ligand 14
DACH1 dachshund family transcription factor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS9 dehydrogenase/reductase (SDR family) member 9
ELOVL2 ELOVL fatty acid elongase 2
FAM171A1 family with sequence similarity 171, member A1
GNAS GNAS complex locus
HEBP1 heme binding protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGHM immunoglobulin heavy constant mu
KDM5D lysine (K)-specific demethylase 5D
LAMP5 lysosomal-associated membrane protein family, member 5
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PHYH phytanoyl-CoA 2-hydroxylase
RHOBTB3 Rho-related BTB domain containing 3
SORBS1 sorbin and SH3 domain containing 1
TGFBI transforming growth factor, beta-induced, 68kDa
ZNF586 zinc finger protein 586