BRD-K32485462_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-K32485462_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C3 complement component 3
CDK14 cyclin-dependent kinase 14
CXADR coxsackie virus and adenovirus receptor
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EIF5A eukaryotic translation initiation factor 5A
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM117A family with sequence similarity 117, member A
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
JUND jun D proto-oncogene
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MSMO1 methylsterol monooxygenase 1
RHOB ras homolog family member B
RPS4Y1 ribosomal protein S4, Y-linked 1
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SHB Src homology 2 domain containing adaptor protein B
SQLE squalene epoxidase
TMEM97 transmembrane protein 97
UBE2J1 ubiquitin-conjugating enzyme E2, J1

decreased expression

Symbol Name
HBEGF heparin-binding EGF-like growth factor
IL1R2 interleukin 1 receptor, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MMP9 matrix metallopeptidase 9
MYBPC1 myosin binding protein C, slow type
UCK2 uridine-cytidine kinase 2