BRD-K32292990_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

20 genes differentially expressed following the BRD-K32292990_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
CDC42 cell division cycle 42
DDIT4 DNA-damage-inducible transcript 4
FOLR1 folate receptor 1 (adult)
GRN granulin
MFAP2 microfibrillar-associated protein 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
EIF5A eukaryotic translation initiation factor 5A
FOSL1 FOS-like antigen 1
IER3 immediate early response 3
INPP1 inositol polyphosphate-1-phosphatase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS2 regulator of G-protein signaling 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM158 transmembrane protein 158 (gene/pseudogene)