BRD-K32238524_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

105 genes differentially expressed following the BRD-K32238524_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AMPD3 adenosine monophosphate deaminase 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCHE butyrylcholinesterase
C6ORF48 chromosome 6 open reading frame 48
CCL5 chemokine (C-C motif) ligand 5
CCND2 cyclin D2
CDK6 cyclin-dependent kinase 6
CDKN2A cyclin-dependent kinase inhibitor 2A
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHODL chondrolectin
CLGN calmegin
COL4A5 collagen, type IV, alpha 5
DDIT4 DNA-damage-inducible transcript 4
ETV1 ets variant 1
FAM129A family with sequence similarity 129, member A
FAM63A family with sequence similarity 63, member A
FBN2 fibrillin 2
FBXL12 F-box and leucine-rich repeat protein 12
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HBD hemoglobin, delta
IL32 interleukin 32
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTB lymphotoxin beta (TNF superfamily, member 3)
LYPD1 LY6/PLAUR domain containing 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP9 matrix metallopeptidase 9
MTSS1 metastasis suppressor 1
PRKCQ protein kinase C, theta
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB4A RAB4A, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
SCG5 secretogranin V
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SOD2 superoxide dismutase 2, mitochondrial
SPON2 spondin 2, extracellular matrix protein
TRD T cell receptor delta locus
TSC22D1 TSC22 domain family, member 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIRF adipogenesis regulatory factor
AGR2 anterior gradient 2
AHR aryl hydrocarbon receptor
AKR1C3 aldo-keto reductase family 1, member C3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD200 CD200 molecule
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CDCA4 cell division cycle associated 4
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COLEC11 collectin sub-family member 11
DKK1 dickkopf WNT signaling pathway inhibitor 1
EMP1 epithelial membrane protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPS8 epidermal growth factor receptor pathway substrate 8
FBP1 fructose-1,6-bisphosphatase 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FZD7 frizzled class receptor 7
GPNMB glycoprotein (transmembrane) nmb
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSTA1 glutathione S-transferase alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IGFBP6 insulin-like growth factor binding protein 6
IGL immunoglobulin lambda locus
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KRT19 keratin 19, type I
KYNU kynureninase
LGALS3 lectin, galactoside-binding, soluble, 3
MAP7 microtubule-associated protein 7
MGLL monoglyceride lipase
MYH11 myosin, heavy chain 11, smooth muscle
MYO1B myosin IB
NPR3 natriuretic peptide receptor 3
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLAC8 placenta-specific 8
PODXL podocalyxin-like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSCA prostate stem cell antigen
RHOBTB3 Rho-related BTB domain containing 3
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SATB1 SATB homeobox 1
SDC1 syndecan 1
SDC4 syndecan 4
SFN stratifin
SWAP70 SWAP switching B-cell complex 70kDa subunit
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8
UBE2G2 ubiquitin-conjugating enzyme E2G 2
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
ZNF652 zinc finger protein 652