BRD-K32101742_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

67 genes differentially expressed following the BRD-K32101742_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARG2 arginase 2
C10ORF10 chromosome 10 open reading frame 10
CD24 CD24 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CSTA cystatin A (stefin A)
CXADR coxsackie virus and adenovirus receptor
DCLK1 doublecortin-like kinase 1
DCT dopachrome tautomerase
DDIT4 DNA-damage-inducible transcript 4
DEGS1 delta(4)-desaturase, sphingolipid 1
EPAS1 endothelial PAS domain protein 1
GPM6B glycoprotein M6B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXA10 homeobox A10
HSPG2 heparan sulfate proteoglycan 2
IGF1 insulin-like growth factor 1 (somatomedin C)
LUM lumican
MMD monocyte to macrophage differentiation-associated
MME membrane metallo-endopeptidase
NEFH neurofilament, heavy polypeptide
OLFM4 olfactomedin 4
PEG10 paternally expressed 10
PLK2 polo-like kinase 2
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKCDBP protein kinase C, delta binding protein
PTN pleiotrophin
RAB27A RAB27A, member RAS oncogene family
RGCC regulator of cell cycle
RTN2 reticulon 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TUBB2A tubulin, beta 2A class IIa
TYRP1 tyrosinase-related protein 1

decreased expression

Symbol Name
AGR2 anterior gradient 2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AXL AXL receptor tyrosine kinase
BST2 bone marrow stromal cell antigen 2
CDCA4 cell division cycle associated 4
COL5A2 collagen, type V, alpha 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRISP3 cysteine-rich secretory protein 3
DUSP5 dual specificity phosphatase 5
ESR1 estrogen receptor 1
FAM8A1 family with sequence similarity 8, member A1
GLUL glutamate-ammonia ligase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HOPX HOP homeobox
INHBA inhibin, beta A
ISG15 ISG15 ubiquitin-like modifier
KIAA0125 KIAA0125
KLF10 Kruppel-like factor 10
KRT7 keratin 7, type II
LAMP5 lysosomal-associated membrane protein family, member 5
MAP7 microtubule-associated protein 7
MN1 meningioma (disrupted in balanced translocation) 1
MUC1 mucin 1, cell surface associated
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
POLB polymerase (DNA directed), beta
RBP1 retinol binding protein 1, cellular
RGS4 regulator of G-protein signaling 4
RHOBTB3 Rho-related BTB domain containing 3
SATB1 SATB homeobox 1
SF1 splicing factor 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa