BRD-K32010074_mw-A1-14 BRD-K32010074_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K32010074_mw-A1-14 BRD-K32010074_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM9 ADAM metallopeptidase domain 9
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BCL2A1 BCL2-related protein A1
C5AR1 complement component 5a receptor 1
CAPN2 calpain 2, (m/II) large subunit
CAV2 caveolin 2
CD9 CD9 molecule
CES1 carboxylesterase 1
CSNK1A1 casein kinase 1, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
EMP1 epithelial membrane protein 1
FOSL1 FOS-like antigen 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HSPA1A heat shock 70kDa protein 1A
IRS2 insulin receptor substrate 2
KRT17 keratin 17, type I
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MEGF9 multiple EGF-like-domains 9
MSLN mesothelin
MT2A metallothionein 2A
NPR3 natriuretic peptide receptor 3
NQO1 NAD(P)H dehydrogenase, quinone 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SFTPB surfactant protein B
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SMAD3 SMAD family member 3
TKT transketolase
TM4SF1 transmembrane 4 L six family member 1
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ACAA1 acetyl-CoA acyltransferase 1
ANGPT1 angiopoietin 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BEX4 brain expressed, X-linked 4
CALB1 calbindin 1, 28kDa
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFH complement factor H
CORO1A coronin, actin binding protein, 1A
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
DLK1 delta-like 1 homolog (Drosophila)
FGFR3 fibroblast growth factor receptor 3
FRZB frizzled-related protein
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
LTF lactotransferrin
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
NID2 nidogen 2 (osteonidogen)
OSR2 odd-skipped related transciption factor 2
PDGFD platelet derived growth factor D
PEG3 paternally expressed 3
PLEKHA5 pleckstrin homology domain containing, family A member 5
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
QPRT quinolinate phosphoribosyltransferase
RELN reelin
RNASE4 ribonuclease, RNase A family, 4
RNASET2 ribonuclease T2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SNX7 sorting nexin 7
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPP1 secreted phosphoprotein 1
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TPD52L1 tumor protein D52-like 1
WFDC2 WAP four-disulfide core domain 2
ZNF91 zinc finger protein 91