BRD-K32010074_mw-A1-14 BRD-K32010074_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K32010074_mw-A1-14 BRD-K32010074_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD46 ankyrin repeat domain 46
AQP1 aquaporin 1 (Colton blood group)
BTG2 BTG family, member 2
CA2 carbonic anhydrase II
CD40 CD40 molecule, TNF receptor superfamily member 5
CEP57 centrosomal protein 57kDa
COL3A1 collagen, type III, alpha 1
CXCL14 chemokine (C-X-C motif) ligand 14
EPAS1 endothelial PAS domain protein 1
EXT1 exostosin glycosyltransferase 1
FAM69A family with sequence similarity 69, member A
FCGBP Fc fragment of IgG binding protein
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GRB7 growth factor receptor-bound protein 7
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JAG1 jagged 1
MFAP2 microfibrillar-associated protein 2
MMP2 matrix metallopeptidase 2
MYO1D myosin ID
NEB nebulin
RGS1 regulator of G-protein signaling 1
SGCE sarcoglycan, epsilon
SPINK1 serine peptidase inhibitor, Kazal type 1
SSPN sarcospan
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIM2 tripartite motif containing 2
TUSC3 tumor suppressor candidate 3
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
AREG amphiregulin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
CD24 CD24 molecule
CLU clusterin
CST3 cystatin C
ELOVL5 ELOVL fatty acid elongase 5
G0S2 G0/G1 switch 2
HOPX HOP homeobox
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LYZ lysozyme
MARCKSL1 MARCKS-like 1
NEFH neurofilament, heavy polypeptide
OSBPL8 oxysterol binding protein-like 8
PEG3 paternally expressed 3
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PRKCH protein kinase C, eta
PTGES prostaglandin E synthase
RHOB ras homolog family member B
S100A6 S100 calcium binding protein A6
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC2 syndecan 2
SELL selectin L
SFN stratifin
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SORD sorbitol dehydrogenase
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TFF1 trefoil factor 1
TNC tenascin C
VLDLR very low density lipoprotein receptor
ZBTB38 zinc finger and BTB domain containing 38