BRD-K32010074_mw-A1-14 BRD-K32010074_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

60 genes differentially expressed following the BRD-K32010074_mw-A1-14 BRD-K32010074_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BMP6 bone morphogenetic protein 6
CA2 carbonic anhydrase II
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CTSZ cathepsin Z
CXADR coxsackie virus and adenovirus receptor
DST dystonin
EIF5 eukaryotic translation initiation factor 5
FHL2 four and a half LIM domains 2
FN1 fibronectin 1
HMOX1 heme oxygenase 1
KCNK1 potassium channel, two pore domain subfamily K, member 1
MFAP2 microfibrillar-associated protein 2
MMP3 matrix metallopeptidase 3
MT1M metallothionein 1M
PBX3 pre-B-cell leukemia homeobox 3
PDGFA platelet-derived growth factor alpha polypeptide
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PSME4 proteasome (prosome, macropain) activator subunit 4
PTPRE protein tyrosine phosphatase, receptor type, E
RBMS1 RNA binding motif, single stranded interacting protein 1
SCG5 secretogranin V
SFN stratifin
SFRP4 secreted frizzled-related protein 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TFF3 trefoil factor 3 (intestinal)
THBS1 thrombospondin 1
TXNRD1 thioredoxin reductase 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
CD200 CD200 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ERBB3 erb-b2 receptor tyrosine kinase 3
GUSBP11 glucuronidase, beta pseudogene 11
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
KDM5D lysine (K)-specific demethylase 5D
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NRN1 neuritin 1
PLK1 polo-like kinase 1
PRPF4 pre-mRNA processing factor 4
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSPH phosphoserine phosphatase
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)