BRD-K31856043_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

106 genes differentially expressed following the BRD-K31856043_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACADVL acyl-CoA dehydrogenase, very long chain
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKR1C3 aldo-keto reductase family 1, member C3
ALDOC aldolase C, fructose-bisphosphate
ASPH aspartate beta-hydroxylase
C1R complement component 1, r subcomponent
C1RL complement component 1, r subcomponent-like
CD163 CD163 molecule
CD99 CD99 molecule
CFD complement factor D (adipsin)
CLIC5 chloride intracellular channel 5
COL1A1 collagen, type I, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ECH1 enoyl CoA hydratase 1, peroxisomal
ENO2 enolase 2 (gamma, neuronal)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FCGBP Fc fragment of IgG binding protein
FN1 fibronectin 1
FOXO4 forkhead box O4
FSD1 fibronectin type III and SPRY domain containing 1
FTH1 ferritin, heavy polypeptide 1
GLRX glutaredoxin (thioltransferase)
GPX3 glutathione peroxidase 3
GSTA4 glutathione S-transferase alpha 4
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
IGFBP6 insulin-like growth factor binding protein 6
IL32 interleukin 32
KRT19 keratin 19, type I
MAP1B microtubule-associated protein 1B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MFAP2 microfibrillar-associated protein 2
MSRB2 methionine sulfoxide reductase B2
MSX1 msh homeobox 1
MVP major vault protein
NRCAM neuronal cell adhesion molecule
NUCB2 nucleobindin 2
PAM peptidylglycine alpha-amidating monooxygenase
PEG10 paternally expressed 10
PFKM phosphofructokinase, muscle
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLIN2 perilipin 2
PRSS8 protease, serine, 8
PYGL phosphorylase, glycogen, liver
RNASE4 ribonuclease, RNase A family, 4
RTN2 reticulon 2
S100A14 S100 calcium binding protein A14
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A1 secretoglobin, family 2A, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCPEP1 serine carboxypeptidase 1
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A18 solute carrier family 22, member 18
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SOX11 SRY (sex determining region Y)-box 11
SOX4 SRY (sex determining region Y)-box 4
STMN2 stathmin 2
STXBP1 syntaxin binding protein 1
SYNGR3 synaptogyrin 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TMSB15A thymosin beta 15a
TNNT1 troponin T type 1 (skeletal, slow)
TSC22D1 TSC22 domain family, member 1
TSKU tsukushi, small leucine rich proteoglycan
TSPAN7 tetraspanin 7
TXNIP thioredoxin interacting protein
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VAT1 vesicle amine transport 1
WISP2 WNT1 inducible signaling pathway protein 2

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ATF5 activating transcription factor 5
BRCA1 breast cancer 1, early onset
CCNE2 cyclin E2
CDC45 cell division cycle 45
CEP55 centrosomal protein 55kDa
FGFR3 fibroblast growth factor receptor 3
GCAT glycine C-acetyltransferase
GINS2 GINS complex subunit 2 (Psf2 homolog)
GRWD1 glutamate-rich WD repeat containing 1
HHEX hematopoietically expressed homeobox
HIST1H4C histone cluster 1, H4c
KANK1 KN motif and ankyrin repeat domains 1
LMNB2 lamin B2
MSMB microseminoprotein, beta-
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPIF peptidylprolyl isomerase F
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RFC2 replication factor C (activator 1) 2, 40kDa
SLBP stem-loop binding protein
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TOR1A torsin family 1, member A (torsin A)