BRD-K31706415_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K31706415_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ASNS asparagine synthetase (glutamine-hydrolyzing)
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
CARS cysteinyl-tRNA synthetase
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EGR1 early growth response 1
ELOVL5 ELOVL fatty acid elongase 5
EPRS glutamyl-prolyl-tRNA synthetase
F3 coagulation factor III (thromboplastin, tissue factor)
FADS1 fatty acid desaturase 1
FBN2 fibrillin 2
FOXO3 forkhead box O3
G0S2 G0/G1 switch 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45A growth arrest and DNA-damage-inducible, alpha
GFPT1 glutamine--fructose-6-phosphate transaminase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA13 heat shock protein 70kDa family, member 13
IDI1 isopentenyl-diphosphate delta isomerase 1
IFRD1 interferon-related developmental regulator 1
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
KDM5D lysine (K)-specific demethylase 5D
LDLR low density lipoprotein receptor
LXN latexin
MCL1 myeloid cell leukemia 1
MSMO1 methylsterol monooxygenase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHLDA1 pleckstrin homology-like domain, family A, member 1
RABAC1 Rab acceptor 1 (prenylated)
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERP1 stress-associated endoplasmic reticulum protein 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SLC35B1 solute carrier family 35, member B1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SQLE squalene epoxidase
TARS threonyl-tRNA synthetase
TES testin LIM domain protein
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TOB1 transducer of ERBB2, 1
TSC22D3 TSC22 domain family, member 3
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UFM1 ubiquitin-fold modifier 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AKAP8 A kinase (PRKA) anchor protein 8
ALB albumin
C3 complement component 3
COLEC12 collectin sub-family member 12
CX3CR1 chemokine (C-X3-C motif) receptor 1
EDN1 endothelin 1
EFNB2 ephrin-B2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GINS1 GINS complex subunit 1 (Psf1 homolog)
GPNMB glycoprotein (transmembrane) nmb
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP7 insulin-like growth factor binding protein 7
NRCAM neuronal cell adhesion molecule
PBX3 pre-B-cell leukemia homeobox 3
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PODXL podocalyxin-like
PTGER4 prostaglandin E receptor 4 (subtype EP4)
XIST X inactive specific transcript (non-protein coding)