BRD-K31688005_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

104 genes differentially expressed following the BRD-K31688005_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGAP29 Rho GTPase activating protein 29
ASCL1 achaete-scute family bHLH transcription factor 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CA2 carbonic anhydrase II
CAMP cathelicidin antimicrobial peptide
CCL4 chemokine (C-C motif) ligand 4
CCND2 cyclin D2
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CLC Charcot-Leyden crystal galectin
CLEC2B C-type lectin domain family 2, member B
COL11A1 collagen, type XI, alpha 1
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CXORF57 chromosome X open reading frame 57
DEFA4 defensin, alpha 4, corticostatin
ERBB4 erb-b2 receptor tyrosine kinase 4
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HHEX hematopoietically expressed homeobox
IGFBP5 insulin-like growth factor binding protein 5
JUP junction plakoglobin
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCTD14 potassium channel tetramerization domain containing 14
KRT19 keratin 19, type I
KRT23 keratin 23, type I
LPAR6 lysophosphatidic acid receptor 6
MEF2C myocyte enhancer factor 2C
MFAP5 microfibrillar associated protein 5
MMP9 matrix metallopeptidase 9
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NPTX2 neuronal pentraxin II
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUPR1 nuclear protein, transcriptional regulator, 1
PEG3 paternally expressed 3
PERP PERP, TP53 apoptosis effector
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PROM1 prominin 1
REEP5 receptor accessory protein 5
RGS5 regulator of G-protein signaling 5
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF44 ring finger protein 44
SOX11 SRY (sex determining region Y)-box 11
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SULF1 sulfatase 1
TERT telomerase reverse transcriptase
TGFA transforming growth factor, alpha
TSPAN12 tetraspanin 12
VAV3 vav 3 guanine nucleotide exchange factor
VNN1 vanin 1
VSNL1 visinin-like 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AK1 adenylate kinase 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ATMIN ATM interactor
BST2 bone marrow stromal cell antigen 2
CAST calpastatin
CDC20 cell division cycle 20
CTSB cathepsin B
DHRS11 dehydrogenase/reductase (SDR family) member 11
DKK1 dickkopf WNT signaling pathway inhibitor 1
ECI2 enoyl-CoA delta isomerase 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBLN1 fibulin 1
FOXO1 forkhead box O1
GADD45B growth arrest and DNA-damage-inducible, beta
GNAS GNAS complex locus
HK1 hexokinase 1
IGFBP4 insulin-like growth factor binding protein 4
IL7R interleukin 7 receptor
KIF14 kinesin family member 14
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LPAR1 lysophosphatidic acid receptor 1
MSRB2 methionine sulfoxide reductase B2
MSX1 msh homeobox 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NES nestin
OLFML3 olfactomedin-like 3
OPN3 opsin 3
PGD phosphogluconate dehydrogenase
PLAC8 placenta-specific 8
PLAT plasminogen activator, tissue
PRDX6 peroxiredoxin 6
PRKCA protein kinase C, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
RCAN1 regulator of calcineurin 1
RHOA ras homolog family member A
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SRPX sushi-repeat containing protein, X-linked
TGM2 transglutaminase 2
TMEM251 transmembrane protein 251
TSPAN3 tetraspanin 3
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UGCG UDP-glucose ceramide glucosyltransferase
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WBSCR22 Williams Beuren syndrome chromosome region 22
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZNF185 zinc finger protein 185 (LIM domain)