BRD-K31412180_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K31412180_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADA adenosine deaminase
AMIGO2 adhesion molecule with Ig-like domain 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL4C ADP-ribosylation factor-like 4C
ARMCX2 armadillo repeat containing, X-linked 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC86 coiled-coil domain containing 86
CD200 CD200 molecule
CD9 CD9 molecule
CD93 CD93 molecule
CDH13 cadherin 13
CHEK1 checkpoint kinase 1
COL8A2 collagen, type VIII, alpha 2
CORO1A coronin, actin binding protein, 1A
CPE carboxypeptidase E
CREB1 cAMP responsive element binding protein 1
CXCL9 chemokine (C-X-C motif) ligand 9
DOCK4 dedicator of cytokinesis 4
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FLT1 fms-related tyrosine kinase 1
GJA1 gap junction protein, alpha 1, 43kDa
GULP1 GULP, engulfment adaptor PTB domain containing 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL1R1 interleukin 1 receptor, type I
KIAA0196 KIAA0196
KRT23 keratin 23, type I
LMO3 LIM domain only 3 (rhombotin-like 2)
LPAR6 lysophosphatidic acid receptor 6
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MMP2 matrix metallopeptidase 2
NPTX2 neuronal pentraxin II
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAPD7 PAP associated domain containing 7
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PRKCI protein kinase C, iota
PRKX protein kinase, X-linked
PXDN peroxidasin
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RND3 Rho family GTPase 3
RSU1 Ras suppressor protein 1
RTN2 reticulon 2
SDC1 syndecan 1
SNX7 sorting nexin 7
SOD2 superoxide dismutase 2, mitochondrial
SOX2 SRY (sex determining region Y)-box 2
SPARCL1 SPARC-like 1 (hevin)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SULF1 sulfatase 1
TCF4 transcription factor 4
TGFB3 transforming growth factor, beta 3
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPSAB1 tryptase alpha/beta 1
TTC39A tetratricopeptide repeat domain 39A
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
AQP3 aquaporin 3 (Gill blood group)
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
COL9A3 collagen, type IX, alpha 3
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSP desmoplakin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM46A family with sequence similarity 46, member A
HN1 hematological and neurological expressed 1
JMJD6 jumonji domain containing 6
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KDM5D lysine (K)-specific demethylase 5D
KIF20A kinesin family member 20A
LTF lactotransferrin
MAMLD1 mastermind-like domain containing 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MSX1 msh homeobox 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
STAT1 signal transducer and activator of transcription 1, 91kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TMBIM6 transmembrane BAX inhibitor motif containing 6