BRD-K30993697_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K30993697_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
COBL cordon-bleu WH2 repeat protein
CORO1C coronin, actin binding protein, 1C
COTL1 coactosin-like F-actin binding protein 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DSE dermatan sulfate epimerase
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
GLRX glutaredoxin (thioltransferase)
HMOX1 heme oxygenase 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPA1A heat shock 70kDa protein 1A
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
KLK10 kallikrein-related peptidase 10
MAPT microtubule-associated protein tau
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NRCAM neuronal cell adhesion molecule
PDGFC platelet derived growth factor C
RAB3B RAB3B, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
TGFBI transforming growth factor, beta-induced, 68kDa
TPD52L1 tumor protein D52-like 1
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
APOLD1 apolipoprotein L domain containing 1
COL3A1 collagen, type III, alpha 1
CTSK cathepsin K
DPT dermatopontin
GATA3 GATA binding protein 3
NFIB nuclear factor I/B
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TYRP1 tyrosinase-related protein 1
XIST X inactive specific transcript (non-protein coding)