BRD-K30993697_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K30993697_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
BHLHE41 basic helix-loop-helix family, member e41
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAST calpastatin
CKB creatine kinase, brain
CLU clusterin
CYCS cytochrome c, somatic
DLK1 delta-like 1 homolog (Drosophila)
DPP4 dipeptidyl-peptidase 4
DUSP5 dual specificity phosphatase 5
FHOD3 formin homology 2 domain containing 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA1A heat shock 70kDa protein 1A
IGKV4-1 immunoglobulin kappa variable 4-1
IL10RA interleukin 10 receptor, alpha
JAG1 jagged 1
LAMP2 lysosomal-associated membrane protein 2
LOC100505650 uncharacterized LOC100505650
MME membrane metallo-endopeptidase
MT1M metallothionein 1M
NEFL neurofilament, light polypeptide
NT5E 5'-nucleotidase, ecto (CD73)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRNP prion protein
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TXNRD1 thioredoxin reductase 1
UBE2L6 ubiquitin-conjugating enzyme E2L 6
XIST X inactive specific transcript (non-protein coding)
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ALOX5AP arachidonate 5-lipoxygenase-activating protein
CD59 CD59 molecule, complement regulatory protein
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLTB clathrin, light chain B
CXCL8 chemokine (C-X-C motif) ligand 8
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GPX3 glutathione peroxidase 3
ITM2A integral membrane protein 2A
PIP prolactin-induced protein
PPARG peroxisome proliferator-activated receptor gamma
PRSS3 protease, serine, 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
REG1A regenerating islet-derived 1 alpha
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TFF3 trefoil factor 3 (intestinal)
TPSAB1 tryptase alpha/beta 1