BRD-K30993697_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

141 genes differentially expressed following the BRD-K30993697_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
BTG2 BTG family, member 2
CA2 carbonic anhydrase II
CCND2 cyclin D2
CCNG2 cyclin G2
CD200 CD200 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPU centromere protein U
CKS2 CDC28 protein kinase regulatory subunit 2
COL11A1 collagen, type XI, alpha 1
CPD carboxypeptidase D
CPE carboxypeptidase E
CTH cystathionine gamma-lyase
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
FAM69A family with sequence similarity 69, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRMD4B FERM domain containing 4B
GATA2 GATA binding protein 2
GLA galactosidase, alpha
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
INSIG1 insulin induced gene 1
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KLHL21 kelch-like family member 21
LEF1 lymphoid enhancer-binding factor 1
LOC100505650 uncharacterized LOC100505650
MAN1A1 mannosidase, alpha, class 1A, member 1
MOSPD1 motile sperm domain containing 1
MTSS1 metastasis suppressor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUPL1 nucleoporin like 1
ODC1 ornithine decarboxylase 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RB1CC1 RB1-inducible coiled-coil 1
RGCC regulator of cell cycle
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RIOK3 RIO kinase 3
RYBP RING1 and YY1 binding protein
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SIK1 salt-inducible kinase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SQLE squalene epoxidase
TBPL1 TBP-like 1
THBD thrombomodulin
TOX3 TOX high mobility group box family member 3
TXNL4B thioredoxin-like 4B
VEGFA vascular endothelial growth factor A
XBP1 X-box binding protein 1
XIST X inactive specific transcript (non-protein coding)
ZBTB11 zinc finger and BTB domain containing 11

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ALCAM activated leukocyte cell adhesion molecule
ASL argininosuccinate lyase
AUTS2 autism susceptibility candidate 2
B3GNT1
BAX BCL2-associated X protein
CALB1 calbindin 1, 28kDa
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CDC25B cell division cycle 25B
CLIP2 CAP-GLY domain containing linker protein 2
CPVL carboxypeptidase, vitellogenic-like
CSK c-src tyrosine kinase
CTSC cathepsin C
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLC1 DLC1 Rho GTPase activating protein
DNM1 dynamin 1
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPN2 epsin 2
ERBB2 erb-b2 receptor tyrosine kinase 2
FOLR1 folate receptor 1 (adult)
GLS glutaminase
GOLGA8B golgin A8 family, member B
HOXA10 homeobox A10
HOXC10 homeobox C10
HOXC6 homeobox C6
KDM5D lysine (K)-specific demethylase 5D
KIAA0100 KIAA0100
MAGED1 melanoma antigen family D1
MRPS2 mitochondrial ribosomal protein S2
MSL1 male-specific lethal 1 homolog (Drosophila)
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PDLIM2 PDZ and LIM domain 2 (mystique)
PENK proenkephalin
PLEC plectin
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SMAD3 SMAD family member 3
SORBS3 sorbin and SH3 domain containing 3
SPATA20 spermatogenesis associated 20
SRI sorcin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TRRAP transformation/transcription domain-associated protein
UPK1B uroplakin 1B