BRD-K30849099_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-K30849099_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARMCX1 armadillo repeat containing, X-linked 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCL20 chemokine (C-C motif) ligand 20
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
EDN1 endothelin 1
EIF5A eukaryotic translation initiation factor 5A
FLNA filamin A, alpha
G0S2 G0/G1 switch 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
JUP junction plakoglobin
KLF10 Kruppel-like factor 10
KRT7 keratin 7, type II
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MYO1B myosin IB
NAV2 neuron navigator 2
NPY1R neuropeptide Y receptor Y1
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PIEZO1 piezo-type mechanosensitive ion channel component 1
PLSCR3 phospholipid scramblase 3
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
RNF167 ring finger protein 167
SMYD2 SET and MYND domain containing 2
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TXNDC9 thioredoxin domain containing 9

decreased expression

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADAM28 ADAM metallopeptidase domain 28
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADIRF adipogenesis regulatory factor
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
C1S complement component 1, s subcomponent
CCL2 chemokine (C-C motif) ligand 2
CD200 CD200 molecule
CDC45 cell division cycle 45
CLIC4 chloride intracellular channel 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DACH1 dachshund family transcription factor 1
DCN decorin
DERA deoxyribose-phosphate aldolase (putative)
DPYSL3 dihydropyrimidinase-like 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERAP2 endoplasmic reticulum aminopeptidase 2
EZR ezrin
FOXF1 forkhead box F1
GSTA1 glutathione S-transferase alpha 1
H3F3B H3 histone, family 3B (H3.3B)
HOXA5 homeobox A5
HSPB8 heat shock 22kDa protein 8
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP6 insulin-like growth factor binding protein 6
KLF4 Kruppel-like factor 4 (gut)
LAMA4 laminin, alpha 4
LGALS2 lectin, galactoside-binding, soluble, 2
LOC100505650 uncharacterized LOC100505650
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP3K5 mitogen-activated protein kinase kinase kinase 5
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MYH11 myosin, heavy chain 11, smooth muscle
PDZK1 PDZ domain containing 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PMP22 peripheral myelin protein 22
PPAP2A phosphatidic acid phosphatase type 2A
PRAME preferentially expressed antigen in melanoma
PTGDS prostaglandin D2 synthase 21kDa (brain)
RGS1 regulator of G-protein signaling 1
RUFY3 RUN and FYVE domain containing 3
SASH1 SAM and SH3 domain containing 1
SCRG1 stimulator of chondrogenesis 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPON1 spondin 1, extracellular matrix protein
TCF4 transcription factor 4
TMEM47 transmembrane protein 47
ZBTB20 zinc finger and BTB domain containing 20