BRD-K30802967_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K30802967_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
ACPP acid phosphatase, prostate
ADAMDEC1 ADAM-like, decysin 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX5 arachidonate 5-lipoxygenase
ARG2 arginase 2
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
BID BH3 interacting domain death agonist
CA2 carbonic anhydrase II
CCDC86 coiled-coil domain containing 86
CD1E CD1e molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CHMP4A charged multivesicular body protein 4A
CKB creatine kinase, brain
CLEC10A C-type lectin domain family 10, member A
CLEC4A C-type lectin domain family 4, member A
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSTA cystatin A (stefin A)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DES desmin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FADS1 fatty acid desaturase 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FOXF1 forkhead box F1
H1F0 H1 histone family, member 0
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HSPA1A heat shock 70kDa protein 1A
IL10RA interleukin 10 receptor, alpha
IL13RA1 interleukin 13 receptor, alpha 1
IL1R1 interleukin 1 receptor, type I
ITM2C integral membrane protein 2C
JAG1 jagged 1
LPAR6 lysophosphatidic acid receptor 6
LXN latexin
LYZ lysozyme
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP12 matrix metallopeptidase 12
MSMB microseminoprotein, beta-
MT1M metallothionein 1M
MX1 MX dynamin-like GTPase 1
NEFH neurofilament, heavy polypeptide
NR1H2 nuclear receptor subfamily 1, group H, member 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
OLFM4 olfactomedin 4
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCP4 Purkinje cell protein 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLSCR1 phospholipid scramblase 1
QPCT glutaminyl-peptide cyclotransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RTN1 reticulon 1
RTN2 reticulon 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
TACC2 transforming, acidic coiled-coil containing protein 2
TGFBI transforming growth factor, beta-induced, 68kDa
THEMIS2 thymocyte selection associated family member 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM2 tripartite motif containing 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

decreased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BST2 bone marrow stromal cell antigen 2
CD59 CD59 molecule, complement regulatory protein
CP ceruloplasmin (ferroxidase)
FAM3C family with sequence similarity 3, member C
GPRC5A G protein-coupled receptor, class C, group 5, member A
IGKC immunoglobulin kappa constant
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
KIF20A kinesin family member 20A
MET MET proto-oncogene, receptor tyrosine kinase
MUC1 mucin 1, cell surface associated
NUP62 nucleoporin 62kDa
PLS3 plastin 3
PODXL podocalyxin-like
PRDX4 peroxiredoxin 4
RHOBTB3 Rho-related BTB domain containing 3
S100A7 S100 calcium binding protein A7
STK26 serine/threonine protein kinase 26
SYBU syntabulin (syntaxin-interacting)
TSKU tsukushi, small leucine rich proteoglycan
ZIC1 Zic family member 1
ZNF395 zinc finger protein 395