BRD-K30632436_CTB_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K30632436_CTB_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA5 annexin A5
AREG amphiregulin
BAG2 BCL2-associated athanogene 2
BIK BCL2-interacting killer (apoptosis-inducing)
CADM1 cell adhesion molecule 1
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
EGLN3 egl-9 family hypoxia-inducible factor 3
FAM46A family with sequence similarity 46, member A
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAS1 growth arrest-specific 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
KIAA0100 KIAA0100
KYNU kynureninase
LAMA3 laminin, alpha 3
LAMP5 lysosomal-associated membrane protein family, member 5
MFAP2 microfibrillar-associated protein 2
MYO6 myosin VI
PEG10 paternally expressed 10
PTN pleiotrophin
RTN2 reticulon 2
S100A10 S100 calcium binding protein A10
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SMAD3 SMAD family member 3
SPATS2L spermatogenesis associated, serine-rich 2-like
TAC1 tachykinin, precursor 1
THBS4 thrombospondin 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TOMM34 translocase of outer mitochondrial membrane 34
TPBG trophoblast glycoprotein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VTCN1 V-set domain containing T cell activation inhibitor 1
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARG1 arginase 1
ASS1 argininosuccinate synthase 1
BID BH3 interacting domain death agonist
C3 complement component 3
CA2 carbonic anhydrase II
COL13A1 collagen, type XIII, alpha 1
CPB2 carboxypeptidase B2 (plasma)
CXADR coxsackie virus and adenovirus receptor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DEGS1 delta(4)-desaturase, sphingolipid 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
IGFBP1 insulin-like growth factor binding protein 1
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
KDM5D lysine (K)-specific demethylase 5D
LBP lipopolysaccharide binding protein
LEF1 lymphoid enhancer-binding factor 1
MAOA monoamine oxidase A
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MXRA5 matrix-remodelling associated 5
PDZK1IP1 PDZK1 interacting protein 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAT plasminogen activator, tissue
PSAT1 phosphoserine aminotransferase 1
PXMP2 peroxisomal membrane protein 2, 22kDa
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SGK1 serum/glucocorticoid regulated kinase 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRGN serglycin
SYPL1 synaptophysin-like 1
VSNL1 visinin-like 1
WT1 Wilms tumor 1
ZMYM2 zinc finger, MYM-type 2