BRD-K30523950_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K30523950_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
CALML3 calmodulin-like 3
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
EMX2 empty spiracles homeobox 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GAA glucosidase, alpha; acid
H1F0 H1 histone family, member 0
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MKNK1 MAP kinase interacting serine/threonine kinase 1
MTA1 metastasis associated 1
PSAT1 phosphoserine aminotransferase 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TNS3 tensin 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ADGRF5 adhesion G protein-coupled receptor F5
AKAP12 A kinase (PRKA) anchor protein 12
ANXA1 annexin A1
CBFB core-binding factor, beta subunit
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
EPCAM epithelial cell adhesion molecule
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
HOMER1 homer scaffolding protein 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
ICAM2 intercellular adhesion molecule 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
ITM2A integral membrane protein 2A
LRRC17 leucine rich repeat containing 17
LXN latexin
MAN1A1 mannosidase, alpha, class 1A, member 1
METTL7A methyltransferase like 7A
MGP matrix Gla protein
MPZL2 myelin protein zero-like 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
RGS4 regulator of G-protein signaling 4
RGS5 regulator of G-protein signaling 5
SCG5 secretogranin V
SFRP1 secreted frizzled-related protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SMS spermine synthase
SNAI2 snail family zinc finger 2
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TUBB6 tubulin, beta 6 class V