BRD-K30351863_NCGC00185090-03_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K30351863_NCGC00185090-03_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD10 ankyrin repeat domain 10
BAG3 BCL2-associated athanogene 3
CD99 CD99 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN10 claudin 10
COL4A5 collagen, type IV, alpha 5
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FBLN2 fibulin 2
FERMT2 fermitin family member 2
FGG fibrinogen gamma chain
GADD45B growth arrest and DNA-damage-inducible, beta
GATA2 GATA binding protein 2
GPX3 glutathione peroxidase 3
HSDL2 hydroxysteroid dehydrogenase like 2
IFI27 interferon, alpha-inducible protein 27
QKI QKI, KH domain containing, RNA binding
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
BOP1 block of proliferation 1
CCDC85B coiled-coil domain containing 85B
CCND1 cyclin D1
CD200 CD200 molecule
DOCK10 dedicator of cytokinesis 10
DST dystonin
EIF1AX eukaryotic translation initiation factor 1A, X-linked
FAM57A family with sequence similarity 57, member A
FAS Fas cell surface death receptor
FCGBP Fc fragment of IgG binding protein
FHL2 four and a half LIM domains 2
GABPB1 GA binding protein transcription factor, beta subunit 1
GPR183 G protein-coupled receptor 183
KRT15 keratin 15, type I
MCL1 myeloid cell leukemia 1
MLPH melanophilin
MSLN mesothelin
MYC v-myc avian myelocytomatosis viral oncogene homolog
OLFM4 olfactomedin 4
PDE4B phosphodiesterase 4B, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RANBP2 RAN binding protein 2
RGS1 regulator of G-protein signaling 1
RPL10 ribosomal protein L10
RPL37A ribosomal protein L37a
SFRP1 secreted frizzled-related protein 1
SRSF2 serine/arginine-rich splicing factor 2
UCK2 uridine-cytidine kinase 2