BRD-K30020243_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K30020243_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CCL20 chemokine (C-C motif) ligand 20
CD47 CD47 molecule
CD52 CD52 molecule
CLIC5 chloride intracellular channel 5
CSTA cystatin A (stefin A)
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
HIST1H1C histone cluster 1, H1c
HMGA1 high mobility group AT-hook 1
MAOA monoamine oxidase A
PCSK5 proprotein convertase subtilisin/kexin type 5
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
RPS4Y1 ribosomal protein S4, Y-linked 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

decreased expression

Symbol Name
APOD apolipoprotein D
CCND1 cyclin D1
CNPY3 canopy FGF signaling regulator 3
COL4A2 collagen, type IV, alpha 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
GATA3 GATA binding protein 3
HSPB8 heat shock 22kDa protein 8
IGF1R insulin-like growth factor 1 receptor
IGFBP4 insulin-like growth factor binding protein 4
KRT14 keratin 14, type I
KRT6B keratin 6B, type II
MARCKS myristoylated alanine-rich protein kinase C substrate
MLPH melanophilin
PFN2 profilin 2
PXDN peroxidasin
TFF1 trefoil factor 1
TMEM176B transmembrane protein 176B
TTC39A tetratricopeptide repeat domain 39A