BRD-K29983336_rondual-kinase-inhibitor_PC3_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K29983336_rondual-kinase-inhibitor_PC3_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
BASP1 brain abundant, membrane attached signal protein 1
CD24 CD24 molecule
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLDN7 claudin 7
CYBA cytochrome b-245, alpha polypeptide
FAM46A family with sequence similarity 46, member A
GPM6B glycoprotein M6B
GRB10 growth factor receptor-bound protein 10
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IRS2 insulin receptor substrate 2
KCNK1 potassium channel, two pore domain subfamily K, member 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1C1 mannosidase, alpha, class 1C, member 1
MFAP5 microfibrillar associated protein 5
MT1E metallothionein 1E
NCALD neurocalcin delta
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPY1R neuropeptide Y receptor Y1
NRCAM neuronal cell adhesion molecule
PDGFRL platelet-derived growth factor receptor-like
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
SFN stratifin
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
WASL Wiskott-Aldrich syndrome-like
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
ANXA3 annexin A3
APOC1 apolipoprotein C-I
BACE2 beta-site APP-cleaving enzyme 2
CCNE2 cyclin E2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CTSH cathepsin H
DEFB1 defensin, beta 1
DSC3 desmocollin 3
HAT1 histone acetyltransferase 1
IGL immunoglobulin lambda locus
IPO13 importin 13
MET MET proto-oncogene, receptor tyrosine kinase
MOK MOK protein kinase
NPTX2 neuronal pentraxin II
PLAC8 placenta-specific 8
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RBP1 retinol binding protein 1, cellular
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TLK2 tousled-like kinase 2
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TXNL4B thioredoxin-like 4B