BRD-K29983336_rondual-kinase-inhibitor_HT29_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K29983336_rondual-kinase-inhibitor_HT29_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD10 ankyrin repeat domain 10
ARHGAP44 Rho GTPase activating protein 44
ASS1 argininosuccinate synthase 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG2 BTG family, member 2
CAPG capping protein (actin filament), gelsolin-like
CES1 carboxylesterase 1
CHN2 chimerin 2
CLU clusterin
CTSA cathepsin A
CYB5R2 cytochrome b5 reductase 2
ELF5 E74-like factor 5 (ets domain transcription factor)
FTH1 ferritin, heavy polypeptide 1
HOOK2 hook microtubule-tethering protein 2
METTL7A methyltransferase like 7A
NFIL3 nuclear factor, interleukin 3 regulated
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRL platelet-derived growth factor receptor-like
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PROM1 prominin 1
RAB25 RAB25, member RAS oncogene family
REEP5 receptor accessory protein 5
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TOX3 TOX high mobility group box family member 3
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BMP2 bone morphogenetic protein 2
C1ORF106 chromosome 1 open reading frame 106
CD69 CD69 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CLEC2B C-type lectin domain family 2, member B
CLIC3 chloride intracellular channel 3
COCH cochlin
CPA3 carboxypeptidase A3 (mast cell)
CXCL9 chemokine (C-X-C motif) ligand 9
EDNRB endothelin receptor type B
GPM6B glycoprotein M6B
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
IFI44L interferon-induced protein 44-like
IGHM immunoglobulin heavy constant mu
IL13RA2 interleukin 13 receptor, alpha 2
MAN1A1 mannosidase, alpha, class 1A, member 1
MYBPC1 myosin binding protein C, slow type
MYLK myosin light chain kinase
NUSAP1 nucleolar and spindle associated protein 1
PAWR PRKC, apoptosis, WT1, regulator
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
PRPF4 pre-mRNA processing factor 4
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
STAT1 signal transducer and activator of transcription 1, 91kDa
TCL1A T-cell leukemia/lymphoma 1A
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TSPYL5 TSPY-like 5
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1