BRD-K29983336_rondual-kinase-inhibitor_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K29983336_rondual-kinase-inhibitor_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA1 annexin A1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BHLHE41 basic helix-loop-helix family, member e41
CADM1 cell adhesion molecule 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
COL5A2 collagen, type V, alpha 2
COMP cartilage oligomeric matrix protein
CPM carboxypeptidase M
CTSZ cathepsin Z
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DMD dystrophin
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
FBXO11 F-box protein 11
GPER1 G protein-coupled estrogen receptor 1
GSE1 Gse1 coiled-coil protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFRD2 interferon-related developmental regulator 2
LGALS3 lectin, galactoside-binding, soluble, 3
LRRC15 leucine rich repeat containing 15
METRN meteorin, glial cell differentiation regulator
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRIP1 nuclear receptor interacting protein 1
NTS neurotensin
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
RBP4 retinol binding protein 4, plasma
SFRP4 secreted frizzled-related protein 4
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SORBS1 sorbin and SH3 domain containing 1
TPD52 tumor protein D52
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
C14ORF2 chromosome 14 open reading frame 2
CCND1 cyclin D1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FBLN5 fibulin 5
FGF13 fibroblast growth factor 13
GDF15 growth differentiation factor 15
HEATR1 HEAT repeat containing 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MGP matrix Gla protein
NFIB nuclear factor I/B
OXA1L oxidase (cytochrome c) assembly 1-like
PFN2 profilin 2
PLIN2 perilipin 2
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRAME preferentially expressed antigen in melanoma
PTGIS prostaglandin I2 (prostacyclin) synthase
RPN1 ribophorin I
SCAND1 SCAN domain containing 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SOX11 SRY (sex determining region Y)-box 11
ZDHHC6 zinc finger, DHHC-type containing 6