BRD-K29950728_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K29950728_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BTG2 BTG family, member 2
CAV1 caveolin 1, caveolae protein, 22kDa
CCNG2 cyclin G2
CD24 CD24 molecule
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
GPC3 glypican 3
GPX3 glutathione peroxidase 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NSG1 neuron specific gene family member 1
P3H2 prolyl 3-hydroxylase 2
PNOC prepronociceptin
PXDN peroxidasin
SCGB2A2 secretoglobin, family 2A, member 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
CD44 CD44 molecule (Indian blood group)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
KDM5D lysine (K)-specific demethylase 5D
LTBP1 latent transforming growth factor beta binding protein 1
LYZ lysozyme
MMP12 matrix metallopeptidase 12
OLFM4 olfactomedin 4
PRSS23 protease, serine, 23
RPS4Y1 ribosomal protein S4, Y-linked 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPRY2 sprouty homolog 2 (Drosophila)
TOX3 TOX high mobility group box family member 3
TSKU tsukushi, small leucine rich proteoglycan