BRD-K29506255_NCGC00185087-01_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K29506255_NCGC00185087-01_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ATF3 activating transcription factor 3
CDC42 cell division cycle 42
CELF2 CUGBP, Elav-like family member 2
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
ECM1 extracellular matrix protein 1
ELOVL4 ELOVL fatty acid elongase 4
EMP1 epithelial membrane protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FEM1B fem-1 homolog b (C. elegans)
FN1 fibronectin 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GTPBP8 GTP-binding protein 8 (putative)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H4C histone cluster 1, H4c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPA1A heat shock 70kDa protein 1A
IDS iduronate 2-sulfatase
IL1RN interleukin 1 receptor antagonist
JAG1 jagged 1
NCF2 neutrophil cytosolic factor 2
NRIP1 nuclear receptor interacting protein 1
ORM1 orosomucoid 1
PELI1 pellino E3 ubiquitin protein ligase 1
QKI QKI, KH domain containing, RNA binding
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RYBP RING1 and YY1 binding protein
S100A7 S100 calcium binding protein A7
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
TACSTD2 tumor-associated calcium signal transducer 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
BHLHE41 basic helix-loop-helix family, member e41
CDC25B cell division cycle 25B
CXCL5 chemokine (C-X-C motif) ligand 5
DENND2D DENN/MADD domain containing 2D
DHRS2 dehydrogenase/reductase (SDR family) member 2
DST dystonin
ETV5 ets variant 5
FAM46A family with sequence similarity 46, member A
FHL2 four and a half LIM domains 2
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GNAS GNAS complex locus
JADE2 jade family PHD finger 2
JMJD6 jumonji domain containing 6
MACF1 microtubule-actin crosslinking factor 1
NMT1 N-myristoyltransferase 1
PFKP phosphofructokinase, platelet
PLA2G16 phospholipase A2, group XVI
PPARG peroxisome proliferator-activated receptor gamma
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS2 regulator of G-protein signaling 2
SCG5 secretogranin V
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TGFBR3 transforming growth factor, beta receptor III
TMEM5 transmembrane protein 5
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8
UBE3C ubiquitin protein ligase E3C
ZHX2 zinc fingers and homeoboxes 2