BRD-K29415052_NVP-BGT226_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

118 genes differentially expressed following the BRD-K29415052_NVP-BGT226_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMOTL2 angiomotin like 2
ATP9A ATPase, class II, type 9A
BHLHE41 basic helix-loop-helix family, member e41
C1RL complement component 1, r subcomponent-like
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDK19 cyclin-dependent kinase 19
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CTGF connective tissue growth factor
CTSB cathepsin B
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOCK9 dedicator of cytokinesis 9
DUOX2 dual oxidase 2
FAM69A family with sequence similarity 69, member A
FUCA1 fucosidase, alpha-L- 1, tissue
GADD45B growth arrest and DNA-damage-inducible, beta
GRN granulin
GRWD1 glutamate-rich WD repeat containing 1
GSN gelsolin
HACD1 3-hydroxyacyl-CoA dehydratase 1
HLA-E major histocompatibility complex, class I, E
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL6ST interleukin 6 signal transducer
IRS2 insulin receptor substrate 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA6 integrin, alpha 6
JAG1 jagged 1
KLF5 Kruppel-like factor 5 (intestinal)
LAMA3 laminin, alpha 3
LAMC2 laminin, gamma 2
LCN2 lipocalin 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOA monoamine oxidase A
MEIS1 Meis homeobox 1
MMP7 matrix metallopeptidase 7
MYO1D myosin ID
NBEA neurobeachin
NCF2 neutrophil cytosolic factor 2
NDFIP1 Nedd4 family interacting protein 1
NET1 neuroepithelial cell transforming 1
OLFM4 olfactomedin 4
OPTN optineurin
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCB4 phospholipase C, beta 4
PRSS23 protease, serine, 23
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOBTB3 Rho-related BTB domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SCG2 secretogranin II
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPP1 selenoprotein P, plasma, 1
SQSTM1 sequestosome 1
STX1A syntaxin 1A (brain)
STXBP1 syntaxin binding protein 1
TGM2 transglutaminase 2
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS3 tensin 3
TSC22D1 TSC22 domain family, member 1
TSKU tsukushi, small leucine rich proteoglycan
TWIST1 twist family bHLH transcription factor 1
VIM vimentin
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACAT1 acetyl-CoA acetyltransferase 1
ADIRF adipogenesis regulatory factor
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BTG3 BTG family, member 3
CD44 CD44 molecule (Indian blood group)
CDC42 cell division cycle 42
CDK1 cyclin-dependent kinase 1
CSRP2 cysteine and glycine-rich protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYB5A cytochrome b5 type A (microsomal)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ECI2 enoyl-CoA delta isomerase 2
EIF5A eukaryotic translation initiation factor 5A
EMP2 epithelial membrane protein 2
ENO1 enolase 1, (alpha)
FEN1 flap structure-specific endonuclease 1
GGCT gamma-glutamylcyclotransferase
GINS2 GINS complex subunit 2 (Psf2 homolog)
GREB1 growth regulation by estrogen in breast cancer 1
HILPDA hypoxia inducible lipid droplet-associated
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSPE1 heat shock 10kDa protein 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
KIAA0101 KIAA0101
LMNB1 lamin B1
MCM3 minichromosome maintenance complex component 3
MYCBP MYC binding protein
NRN1 neuritin 1
PBK PDZ binding kinase
PGK1 phosphoglycerate kinase 1
PHGDH phosphoglycerate dehydrogenase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAD51C RAD51 paralog C
RBX1 ring-box 1, E3 ubiquitin protein ligase
RFC2 replication factor C (activator 1) 2, 40kDa
RGS2 regulator of G-protein signaling 2
RPL39L ribosomal protein L39-like
RRM2 ribonucleotide reductase M2
S100A7 S100 calcium binding protein A7
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
TFDP1 transcription factor Dp-1
TMPO thymopoietin
TMSB15A thymosin beta 15a
TSPYL5 TSPY-like 5
TYMS thymidylate synthetase
VDAC1 voltage-dependent anion channel 1