BRD-K29415052_NVP-BGT226_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

88 genes differentially expressed following the BRD-K29415052_NVP-BGT226_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMDHD2 amidohydrolase domain containing 2
AMIGO2 adhesion molecule with Ig-like domain 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CELF2 CUGBP, Elav-like family member 2
CREBL2 cAMP responsive element binding protein-like 2
CRIP1 cysteine-rich protein 1 (intestinal)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP4 dual specificity phosphatase 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
FAM134A family with sequence similarity 134, member A
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FZD5 frizzled class receptor 5
GADD45B growth arrest and DNA-damage-inducible, beta
HEBP1 heme binding protein 1
IRS2 insulin receptor substrate 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLF7 Kruppel-like factor 7 (ubiquitous)
LAMC2 laminin, gamma 2
LDOC1 leucine zipper, down-regulated in cancer 1
LETMD1 LETM1 domain containing 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MGLL monoglyceride lipase
MNT MAX network transcriptional repressor
NPC1 Niemann-Pick disease, type C1
ORAI3 ORAI calcium release-activated calcium modulator 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SDC4 syndecan 4
SDCBP syndecan binding protein (syntenin)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SQRDL sulfide quinone reductase-like (yeast)
STX1A syntaxin 1A (brain)
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SYT17 synaptotagmin XVII
TGM2 transglutaminase 2
TSC22D3 TSC22 domain family, member 3
VAT1 vesicle amine transport 1
VEGFC vascular endothelial growth factor C

decreased expression

Symbol Name
ASF1B anti-silencing function 1B histone chaperone
AURKB aurora kinase B
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CDC7 cell division cycle 7
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN3 cyclin-dependent kinase inhibitor 3
CEP55 centrosomal protein 55kDa
CNN3 calponin 3, acidic
DHFR dihydrofolate reductase
FANCI Fanconi anemia, complementation group I
FOXM1 forkhead box M1
GCLM glutamate-cysteine ligase, modifier subunit
GINS2 GINS complex subunit 2 (Psf2 homolog)
H2AFX H2A histone family, member X
KIF20A kinesin family member 20A
KIF4A kinesin family member 4A
LIG1 ligase I, DNA, ATP-dependent
LMNB1 lamin B1
LRRC59 leucine rich repeat containing 59
MCM10 minichromosome maintenance complex component 10
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MKI67 marker of proliferation Ki-67
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NCAPG non-SMC condensin I complex, subunit G
OIP5 Opa interacting protein 5
ORC6 origin recognition complex, subunit 6
PBK PDZ binding kinase
PHGDH phosphoglycerate dehydrogenase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PSPH phosphoserine phosphatase
RFC2 replication factor C (activator 1) 2, 40kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
SHCBP1 SHC SH2-domain binding protein 1
SMC4 structural maintenance of chromosomes 4
THBS1 thrombospondin 1
TIMELESS timeless circadian clock
TK1 thymidine kinase 1, soluble
TRIP13 thyroid hormone receptor interactor 13
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
ZWINT ZW10 interacting kinetochore protein