BRD-K29143967_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K29143967_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
BCHE butyrylcholinesterase
BLNK B-cell linker
CCR2 chemokine (C-C motif) receptor 2
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CSTA cystatin A (stefin A)
E2F2 E2F transcription factor 2
HOXB2 homeobox B2
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP5 insulin-like growth factor binding protein 5
LPAR6 lysophosphatidic acid receptor 6
LRRC17 leucine rich repeat containing 17
MEIS2 Meis homeobox 2
MTMR11 myotubularin related protein 11
NR1H2 nuclear receptor subfamily 1, group H, member 2
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCN3A sodium channel, voltage gated, type III alpha subunit
TGFA transforming growth factor, alpha
TMEM35 transmembrane protein 35
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRD T cell receptor delta locus
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ASS1 argininosuccinate synthase 1
BASP1 brain abundant, membrane attached signal protein 1
C6ORF62 chromosome 6 open reading frame 62
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYBA cytochrome b-245, alpha polypeptide
DICER1 dicer 1, ribonuclease type III
EIF4B eukaryotic translation initiation factor 4B
FOLR1 folate receptor 1 (adult)
GAS1 growth arrest-specific 1
GOLGA8A golgin A8 family, member A
HEXIM1 hexamethylene bis-acetamide inducible 1
HIPK1 homeodomain interacting protein kinase 1
ICAM3 intercellular adhesion molecule 3
IL6ST interleukin 6 signal transducer
LYPLA1 lysophospholipase I
MAP7 microtubule-associated protein 7
MBP myelin basic protein
MRPS30 mitochondrial ribosomal protein S30
NRIP1 nuclear receptor interacting protein 1
OXA1L oxidase (cytochrome c) assembly 1-like
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PROS1 protein S (alpha)
PTP4A2 protein tyrosine phosphatase type IVA, member 2
QPRT quinolinate phosphoribosyltransferase
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RPS11 ribosomal protein S11
RPS27L ribosomal protein S27-like
SF1 splicing factor 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SPRY2 sprouty homolog 2 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
SYNJ2 synaptojanin 2
TBC1D4 TBC1 domain family, member 4
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TSPAN3 tetraspanin 3