BRD-K28800414_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

26 genes differentially expressed following the BRD-K28800414_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
FASN fatty acid synthase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
RPS11 ribosomal protein S11
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFRP1 secreted frizzled-related protein 1
SQLE squalene epoxidase
SRPX sushi-repeat containing protein, X-linked
SYBU syntabulin (syntaxin-interacting)
TMC5 transmembrane channel-like 5
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
CA2 carbonic anhydrase II
CLEC2B C-type lectin domain family 2, member B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
PEG10 paternally expressed 10
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPD52L1 tumor protein D52-like 1