BRD-K28578425_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K28578425_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL4C ADP-ribosylation factor-like 4C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX4 brain expressed, X-linked 4
BGN biglycan
BMP4 bone morphogenetic protein 4
CADM1 cell adhesion molecule 1
CALML3 calmodulin-like 3
CD44 CD44 molecule (Indian blood group)
CD48 CD48 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
CRABP2 cellular retinoic acid binding protein 2
DPP4 dipeptidyl-peptidase 4
FST follistatin
GJA1 gap junction protein, alpha 1, 43kDa
IFNAR1 interferon (alpha, beta and omega) receptor 1
KRT23 keratin 23, type I
LPAR6 lysophosphatidic acid receptor 6
MMP13 matrix metallopeptidase 13
PEG10 paternally expressed 10
POSTN periostin, osteoblast specific factor
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTN pleiotrophin
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGCC regulator of cell cycle
RGS16 regulator of G-protein signaling 16
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A1 S100 calcium binding protein A1
SCGB1D2 secretoglobin, family 1D, member 2
SDC2 syndecan 2
SNX7 sorting nexin 7
SULF1 sulfatase 1
THBS2 thrombospondin 2
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TWIST1 twist family bHLH transcription factor 1
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGR2 anterior gradient 2
AKAP7 A kinase (PRKA) anchor protein 7
APOD apolipoprotein D
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BASP1 brain abundant, membrane attached signal protein 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GSN gelsolin
HOXC6 homeobox C6
IGFBP4 insulin-like growth factor binding protein 4
ITM2A integral membrane protein 2A
KANK2 KN motif and ankyrin repeat domains 2
MAP4 microtubule-associated protein 4
MARCKSL1 MARCKS-like 1
NEFL neurofilament, light polypeptide
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIB nuclear factor I/B
NR2F2 nuclear receptor subfamily 2, group F, member 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAGL1 pleiomorphic adenoma gene-like 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SOX4 SRY (sex determining region Y)-box 4
SRPX sushi-repeat containing protein, X-linked
STOM stomatin
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TJP2 tight junction protein 2
TSPAN13 tetraspanin 13
UGCG UDP-glucose ceramide glucosyltransferase